5 years ago

New Drug Shows Hope for Celiac Disease

An early trial for an experimental drug that helps prevent intestinal damage caused by celiac disease shows the drug could be the first to help alleviate the digestive disorder that affects people around the world.

With celiac disease, the immune system attacks the small intestine’s lining when a person eats gluten. Right now, the only treatment course is to remove gluten from a diet.

The drug in the trial would prevent the intestinal damage that leads to symptoms like fatigue, weight loss, and abdominal pain. In the study, patients that were given the drug showed less intestinal damage than those that took the placebo.

Even with gluten-free diets, many patients continue to suffer. “About 30% of patients continue have substantial issues despite doing their best on a gluten-free diet,” Dr. Joseph Murray, a gastroenterologist at the Mayo Clinic, said.

“There is real hope we will have additional treatments for celiac, which heretofore has placed the entire burden of care on the patient,” Murray said.

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