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In the quest for optimal health and well-being, the role of antioxidants cannot be overstated. Among these defenders of cellular health, there’s one mighty warrior that often goes under the radar: glutathione. This remarkable antioxidant, composed of three essential amino acids—glutamine, glycine, and cysteine—plays a pivotal role in safeguarding our bodies against oxidative stress, a culprit behind various chronic conditions, including autoimmune diseases. However, numerous factors, including poor nutrition, environmental toxins, and the relentless march of time, can lead to diminished glutathione levels within our cells.

Fortunately, there’s good news. Increasing your glutathione levels can yield a multitude of health benefits.

  • Reduces Oxidative Stress: Oxidative stress, the result of an imbalance between free radical production and the body’s capacity to counteract them, can be a precursor to various diseases, including diabetes, cancer, and rheumatoid arthritis.
  • May Improve Psoriasis: A small-scale study has shown promising results regarding the potential benefits of whey protein, which can increase glutathione levels, in improving psoriasis symptoms. Participants in the study received a daily oral supplement of 20 grams of whey protein for three months, indicating the need for further research in this area.
  • Reduces Cell Damage in Liver Diseases: Cell death in the liver, which contributes to alcoholic and nonalcoholic fatty liver diseases, can be exacerbated by an antioxidant deficiency, including glutathione. Studies have revealed that glutathione supplementation can ameliorate protein, enzyme, and bilirubin levels in the blood, particularly when administered intravenously or orally following lifestyle changes.
  •  Improves Insulin Resistance in Older Individuals: As we age, our bodies naturally produce less glutathione, potentially leading to weight management challenges and insulin resistance. Research conducted at Baylor School of Medicine uncovered that raising glutathione levels by supplementing with cysteine and glycine improved insulin resistance and fat burning in older individuals.
  • Reduces Symptoms of Parkinson’s Disease: While Parkinson’s disease remains incurable, a notable case report suggests that intravenous glutathione may alleviate symptoms such as tremors and rigidity. More research is needed in this area, but these findings offer hope for improving the quality of life for those living with Parkinson’s.
  • May Help Fight Against Autoimmune Disease: Autoimmune diseases, characterized by chronic inflammation and oxidative stress, can wreak havoc on the body. Glutathione’s ability to reduce oxidative stress by regulating the body’s immune response holds promise for individuals battling autoimmune conditions such as rheumatoid arthritis, celiac disease, and lupus.

1. Fresh Nutrition

Fresh Nutrition Glutathione Supplement Capsule
Fresh Nutrition Glutathione Supplement Capsule

Fresh Nutrition Glutathione Supplement Capsules are vegan, gluten-free, non-GMO, soy-free, and all-natural. This third-party tested bottle comes with 90 capsules for 30 days. It costs $19.97, which is a great price!

Listed as Amazon’s Choice, it has high reviews. One reviewer said, “I began taking this two weeks ago, and I have nothing but good things to say. The capsules are small and easy to swallow; if you’re like me and need capsules for easier absorption, this is the one to buy. I’m starting to feel the effects of taking it daily, and I’m going to take it at night before a meal from now on. It seems to boost my energy. Since I’m older, my body produces less of this. I’m extremely picky with my supplements and this one ticked all the good boxes off. Detox, antioxidant, anti-aging, stronger immune system, and more. My metabolism is slow, so this is one supplement I won’t skip. My immune system is compromised, another reason I love this product. It’s made in the USA so I feel good about my purchase and the contents being all natural.”

2. Supplement Studio

Supplement Studio Liposomal Glutathione
Supplement Studio Liposomal Glutathione

Supplement Studio Liposomal Glutathione supplements are gluten-free, third-party tested, made in the USA, and vegan! A day day supply costs $34.87, which is pricier than others on the market.

It has an overall rating of 4.6 stars, one of which says “I looked at many versions of this vitamin I like the fact that this used raw organic vegetables with nothing synthetic.

I started taking this for fatty liver. My liver has improved dramatically from June to August and I know that because I’m a sonographer and have scans done regularly to check.

I highly recommend this product if you have a fatty liver”

3. Terry Naturally

Terry Naturally Clinical Glutathione
Terry Naturally Clinical Glutathione

Terry Naturally Clinical Glutathione slow melt tablets are vegan, non-GMO, and lab-tested for purity and quality. A 30-day supply costs $67.95, which is definitely on the expensive side.

Kurt M. left a review saying, “At age 83 I have always had a genetic quirk which makes my body unable to recycle its glutathione so My levels are always too low. This in turn reduces my immunity to disease. GET THIS! After just two weeks on 4 tabs daily I was astonished to see that my low-grade psoriasis was diminishing and my lifelong dry skin had changed. Now when I remove my garments I no longer see “snow” falling out of them. For the first time in 70 years, my arms and legs do not look like those of a reptile. I had not anticipated either of these improvements at all. I can assume from these improvements that my immunity has changed for the better too. This should help protect me from COVID. I have tried numerous other glutathione supplements to no avail. This is the answer to my prayers. I suggest you try it for three weeks 2 in the AM and 2 at bedtime. Good luck. Update. 3-23-21 I just received Lab results from a test of my glutathione levels; I came out at 484 on a range scale of 373-838 uM. So it does work. No Covid either. THIS STUFF REALLY WORKS!”

4. VitaRaw

Vita Raw Glutathione Capsules
Vita Raw Glutathione Capsules

VitaRaw Glutathione Capsules are made in the USA, vegan, and two times more potent than oxidized glutathione supplements. The thirty-day supply is $26.08, which is cheaper than others on the market.

It has high ratings with 4.4 stars overall on Amazon. Marcie Lynn Wason said, “Hi there! I’ve been taking this form of glutathione for about 6 months now, and it’s become essential. I feel better, I look better, and because I have severe chronic pain issues this helps with, I function better. Please note that the bottle contains 30 servings of 1000 mg l-glutathione complex, each tablet doesn’t contain 1000 mg of 1-glutathione. That being said, I’ve taken glutathione as well as it’s liposomal form, I’m achieving better results with this l-glutathione, and I’m very happy with the particular blend they have added to it. Since I no longer have to purchase other supplements, I’m actually saving money since I no longer need to buy the supplements that are in this on in addition to the l-glutathione. I have been using milk thistle off and on for 25 years for its neuroprotective and anti-inflammatory after a scooter accident that resulted in a head injury and a badly fractured leg. I’ve been taking lecithin since childhood on the advice of my grandfather who was a doctor, and I began taking MCT oil a few years ago for its numerous benefits.

Like a few others have mentioned, it keeps me regular. I’m not sure what’s going on with that because, as I mentioned above I’ve taken glutathione and the additional ingredients in this supplement, and never experienced anything like it before. Maybe it happened, it just wasn’t as immediate? By immediate I don’t mean that it’s anything like diarrhea.

Anyway, I’m very happy with this addition to my AM supplements. I gave a bottle to my friend who now takes it regularly as well.

Thanks for reading, I hope this helps someone. Take care, everyone!♥️”

5. NOW

NOW Glutathione Supplements
NOW Glutathione Supplements

NOW Glutathione Supplements are vegan and made with milk thistle extract. A 60-day supply costs $21.57, which is a great price considering the amount you receive per bottle!

This is one of the highest-rated glutathione supplements on Amazon with 4.6 stars overall. Robert Carty left a review saying, “I bought the product specifically to lighten scars but at this point, I’m invested to whiten my whole body lol for science.
After one bottle down (finished under a month because I take 3 a day) I haven’t noticed significant skin lightening but my nails are glorious 👌 finger nails and toe nails looking very healthy, and my skin overall seems more hydrated but I wouldn’t say I’m lighter yet. Sometimes I need to poop soon after taking this lol
I have purchased another bottle and will continue to take this to see when my skin begins to lighten. For reference, I’m native American so I have light medium skin, but my overall complexion is closer to that of someone of Hispanic descent. Meaning my face and hands are more pale than my body itself. And my overall skin tone is more olive with yellow undertones.”

6. NutraHarmony

NutraHarmony Glutathione Supplement
NutraHarmony Glutathione Supplement

NutraHarmony Glutathione Supplement capsules are vegan, non-GMO, gluten-free, made in the USA, and free of dye and sugar. Thirty servings cost $22.89.

This is another highly-rated glutathione supplement, with 4.8 stars. One reviewer said, “I’m such a busy person most days I work over 12 hours. This supplement has definitely been a game changer for me and it’s not a part of my daily routine and the supplements I take before I go to the gym. I love that it also aids my immune system as my job requires me to be around people 24/7. There’s a fairly good amount of capsules to last. There’s so many more benefits that this supplement aids the body in. I love it”

7. Code Age

Codeage Liposomal Glutathione
Codeage Liposomal Glutathione

Codeage Liposomal Glutathione is vegan and non-GMO. The bottle comes with 60 capsules, which is a 30-day supply. As Amazon’s Choice, it is on the pricier side at $44.99.

One reviewer said, “I’m really beginning to love Code Age. They have many excellent products. This liposomal glutathione will have superior absorption, which is extremely important because most of it would otherwise be destroyed before the body can use it. Many people supplement with NAC in order to boost glutathione, but NAC supplements are hard to find due to allegations they step on the toes of a big pharma patent. Many people on the autism spectrum anecdotally expressed great improvement in symptoms while taking NAC. Liposomal glutathione may be a more direct alternative to taking NAC. One should always consult their healthcare professional before taking a supplement. I’ve heard a doctor on YouTube caution against too much liposomal glutathione because its superior absorption could lead to too much inside some tissues and organs like the brain. So I consider this a superior product that should be approached with respect and caution.”

8. Guigmiens

Guigmiens Liquid Glutathione Supplement
Guigmiens Liquid Glutathione Supplement

Guigmiens Liquid Glutathione Supplement comes in liquid form to easily be dropped into liquids, like smoothies. Additionally, it is soy-free, non-GMO, vegan, and gluten-free. Thirty servings is $31.99.

Reviewers love this product, Valerie said, “Although we all need it, my primary concern was giving it to my dog who is recovering from a systemic infection. I wanted to make sure it absorbs well when added to her food, but do not have to. I count the drops into a teaspoon and she loves to lick it all up. It tastes great, has no smell, easy to administer, and works great. I give her other needed nutrients as well, and together they do wonders. Her vitality is back, sleeps less, feels good to jump, run, and take long walks, and her symptoms are almost all gone. We are what we eat and glutathione plays a very important role. Must take it for good nutritional balance. I am very happy with this product for it also priced right, and I love the taste of it too.”

9. Nature’s Craft

Nature's Craft Reduced Glutathione Supplement
Nature’s Craft Reduced Glutathione Supplement

Nature’s Craft Reduced Glutathione Supplement is derived from milk thistle. This product is vegan, third-party tested, and made in the USA with globally sourced ingredients. A thirty-day supply is on the cheaper end at $17.79. 

Mike left a review saying, “This is my preferred source of glutathione, I had no problems with consuming it and I believed it worked well with my diet and lifestyle. I recommend this to anyone who is bringing wellness and working a healthy lifestyle with this supplement. I believe that my focus and retention were booted and helped a lot after a few weeks!!”

10. Per Se Labs

Per Se Labs Liposomal Glutathione Liquid
Per Se Labs Liposomal Glutathione Liquid

Per Se Labs Liposomal Glutathione Liquid is gluten free, non-GMO, and vegan. The unflavored liquid bottle has a 2-month supply for $12.99, which is one of the cheapest on the market.

This product does not have the highest reviews, with one reviewer saying, “I’ve started to add Glutathione to my mix of things to take. It is an important antioxidant that is just starting to get more attention in the media.

As others have said, the taste is off-putting, but I see it as “good medicine”. I usually just swallow it quickly and get it out of the way, instead of mixing it in something. It may be better absorbed under the tongue anyway. It is also in liposomal form, which is supposed to increase absorption.

One thing I really like is it is made in the USA. I would like to see the results of 3rd party testing too.”

In conclusion, the pursuit of optimal health often leads us down a path paved with the discoveries of nature’s most formidable defenders, and glutathione stands as a shining beacon in this quest. Increasing your glutathione levels through supplements can unlock a multitude of benefits, ranging from the reduction of oxidative stress and improved liver health to enhanced insulin resistance and mobility for those with specific health conditions.

The ever-growing body of research into the potential of glutathione underscores its importance in safeguarding our well-being. While glutathione is naturally produced within our cells, various factors can deplete its levels, leaving us vulnerable to the ravages of oxidative stress and chronic diseases.

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